Most human cells have 23 pairs of chromosomes. Any deviation from this number can be fatal for cells, and several genetic disorders, such as Down syndrome, are caused by abnormal numbers of chromosomes.
May 13, 2019
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Scientists have identified a genetic mutation that causes a childhood kidney cancer called Wilms' tumour.
May 30, 2017
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Aneuploidy is a condition in which cells contain an abnormal number of chromosomes, and is known to be the cause of many types of cancer and genetic disorders, including Down Syndrome. The condition is also the leading cause ...
Apr 6, 2017
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(Medical Xpress)—A team of researchers at Stanford University has found a gene that increases the rate of maternal aneuploidy in embryos. In their paper published in the journal Science, the team describes how they used ...
For more than 100 years, researchers have been unable to explain why cancer cells contain abnormal numbers of chromosomes, a phenomenon known as aneuploidy. Many believed aneuploidy was simply a random byproduct of cancer.
Oct 31, 2013
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A new molecular pathway involving the gene ZNF365 has been identified and abnormalities in that pathway may predict worse outcomes for patients with breast cancer, according to data published in Cancer Discovery, a journal ...
Jun 17, 2013
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Cohesin is a ring-shaped protein complex involved in the spatial organization of the genome and in mitotic chromosome structure. Vertebrate somatic cells have two versions of cohesin that contain either SA1 or SA2, but their ...
May 3, 2012
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They are the Robinson Crusoes of the intracellular world -- lone chromosomes, whole and hardy, stranded outside the nucleus where their fellow chromosomes reside. Such castaways, each confined to its own "micronucleus," are ...
Jan 19, 2012
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Washington State University researchers have confirmed a critical step in cell division that results in age-related miscarriages and birth defects, including Down syndrome.
Apr 14, 2011
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