Cancer cells with extra chromosomes depend on those chromosomes for tumor growth, a new Yale study reveals, and eliminating them prevents the cells from forming tumors. The findings, said the researchers, suggest that selectively ...
Jul 6, 2023
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The vast majority of cancer cells have too few or too many copies of some chromosomes, a state known as aneuploidy. But for decades, researchers have debated whether aneuploidy promotes the growth of cancers, or is simply ...
Jun 29, 2023
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People with an additional X or Y chromosome—a genetic condition known as supernumerary sex chromosome aneuploidy—have an increased risk of developing blood clots known as venous thromboembolism (VTE), a Geisinger study ...
Jan 25, 2023
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A woman's risk of suffering one of the most common types of miscarriages can be predicted based on a specialized analysis of her genome, according to a Rutgers University study.
Jun 13, 2022
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Scientists have found a genetic mutation that results in cancer cells being able to tolerate having an abnormal number of chromosomes—a condition which normally kills cells—allowing them to adapt to their environment ...
May 9, 2022
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Patients with non-small cell lung cancer (NSCLC) whose cancer cells have low levels of aneuploidy—an abnormal number of chromosomes—tend to respond better to immune checkpoint inhibitor drugs than patients with higher ...
Apr 11, 2021
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Cancer remains the leading cause of death by disease in children and young people in the UK. It's a stark reminder of how much work remains to be done, and why Cancer Research UK (CRUK) is making pediatric cancer a priority. ...
Mar 18, 2021
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What makes cancer cells different from ordinary cells? Can these differences be used to strike at them and paralyze their activity? This basic question has bothered cancer researchers since the mid-19th century. The search ...
Jan 27, 2021
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The presence of an abnormal number of chromosomes in the genetic profile of early-stage embryos may be far more common—and potentially less threatening—during normal human development than is currently appreciated, according ...
Jul 8, 2020
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Cancer cells are notorious for their genetic disarray. A tumor cell can contain an abundance of DNA mutations and most have the wrong number of chromosomes. A missing or extra copy of a single chromosome creates an imbalance ...
Feb 24, 2020
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Aneuploidy is an abnormal number of chromosomes, and is a type of chromosome abnormality. An extra or missing chromosome is a common cause of genetic disorders (birth defects). Some cancer cells also have abnormal numbers of chromosomes. Aneuploidy occurs during cell division when the chromosomes do not separate properly between the two cells. Chromosome abnormalities occur in 1 of 160 live births. The most common extra chromosomes among live births are 21, 18 and 13.
Different species have different numbers of normal chromosomes and thus the term "aneuploidy" refers to the chromosome number being different for that species.
This text uses material from Wikipedia, licensed under CC BY-SA
