Surgery

Optimizing tissue engineering in rotator cuff repair

Retear and failure to heal are significant post-operative complications in rotator cuff repair surgery despite the use of commercially available rotator cuff repair grafts. Advances in tissue engineering have demonstrated ...

Oncology & Cancer

AI accurately predicts cancer outcomes from tissue samples

Researchers at UT Southwestern Medical Center have developed a novel artificial intelligence (AI) model that analyzes the spatial arrangement of cells in tissue samples. This innovative approach, detailed in Nature Communications, ...

Medical research

Prenatal stem cells treat hemophilia A in preclinical study

Researchers at the Wake Forest Institute for Regenerative Medicine (WFIRM) have recently published an article in Nature Communications that demonstrates the potential of bioengineered human placental cells as a cure for Hemophilia ...

Oncology & Cancer

Better cancer diagnosis thanks to digital 3D images

It all started with an innocuous question at the start of Francesca Catto's doctoral thesis: Wouldn't it be nice if tissue samples could be colored and digitally displayed as a 3D image? For more than 100 years, histology, ...

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Tissue engineering

Tissue engineering was once categorised as a subfield of Biomaterials, but having grown in scope and importance it can be considered as a field in its own right. It is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physio-chemical factors to improve or replace biological functions. While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, etc.). Often, the tissues involved require certain mechanical and structural properties for proper functioning. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bioartificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells to produce tissues.

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