Medical research

Scientists build whole functioning thymus from human cells

Researchers at the Francis Crick Institute and University College London have rebuilt a human thymus, an essential organ in the immune system, using human stem cells and a bioengineered scaffold. Their work is an important ...

Genetics

Scientists map genes controlling immune system 'brakes'

Unlike most T cells, which launch immune responses against foreign molecules, regulatory T cells are the peacekeepers of the human immune system, damping down inflammatory reactions when they're not needed. Now, researchers ...

Immunology

Researchers generate developmental map of human T-cells

Chintan Parekh, MD, of the The Saban Research Institute of Children's Hospital Los Angeles, has led a team of investigators that generated a comprehensive roadmap for how T-cells develop in the human thymus. The study will ...

Immunology

Discovery may help kick-start ageing immune system

The thymus is the powerhouse producing the immune system's T cells, which combat infection in our body. Yet this vital organ is one of the first to diminish in function as we age, resulting in a gradual loss of T cell production ...

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