Investigators at Weill Cornell Medicine have assembled the most comprehensive atlas to date of messenger RNA (mRNA) variants in the mouse and human brain. The atlas is an important new resource in understanding brain development, ...
Apr 9, 2024
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Leukemia is the most common type of cancer in children. Treatment involves intensive chemotherapy, which has severe side effects due to its non-specific mode of action.
Nov 20, 2023
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Chromatin states and their associated epigenetic information play a crucial role in maintaining the identity of cells as they divide. Histone post-translational modifications (PTMs) are important determinants of the cellular ...
Jun 16, 2023
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Exposure to opioids under chronic pain conditions produces unique gene expression changes in brain regions associated with cognition, emotion, and reward, according to preclinical research conducted at the Icahn School of ...
Jun 9, 2023
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When cells copy DNA to produce RNA transcripts, they include only some chunks of genetic material known as exons and throw out the rest. The resulting product is a fully-mature RNA molecule, which can be used as a template ...
Feb 9, 2023
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The University of Alabama at Birmingham Marnix E. Heersink School of Medicine's Department of Radiation Oncology researchers have identified potential targets to help overcome therapy-resistant tumors in patients with glioblastoma, ...
Sep 21, 2022
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The microbes that help break down food actually tell the gut how to do its job better, according to a new study in mice at Duke.
May 13, 2022
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Inside embryonic cells, specific proteins control the rate at which genetic information is transcribed from DNA to messenger RNA—a crucial regulatory step before proteins are created. Then, organs develop and hopefully ...
Apr 27, 2022
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Dogs are proving to be a far better scientific model for study of prostate cancer than mice, the typical animal used in the lab for this type of research. In the first use of canines in an advanced prostate cancer study, ...
Feb 7, 2022
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Researchers at Hiroshima University have analyzed the molecular findings of almost 160 pediatric liver cancer cases and discovered molecular markers that should help to understand and treat the considerable variation in prognoses.
Sep 21, 2021
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