Oncology & Cancer
Clearing a path for cancer research
EMBL-EBI researchers have developed a new computational method to study biological signalling networks in healthy and cancer cells.
Sep 10, 2015
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Page 3 - News tagged with protein kinase inhibitors
Oncology & Cancer
Anaplastic lymphoma kinase immunohistochemistry testing comparable to fluorescence in situ hybridization testing
Sixteen institutions across Europe collaborated together to show for the first time that a semi-quantitative anaplastic lymphoma kinase (ALK) protein expression test, immunohistochemistry (IHC), is reliable amongst several ...
Oct 23, 2014
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Medical research
Cancer-fighting drugs might also stop malaria early
Scientists searching for new drugs to fight malaria have identified a number of compounds—some of which are currently in clinical trials to treat cancer—that could add to the anti-malarial arsenal.
Aug 25, 2014
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Medical research
New computational method exploits the polypharmacology of drugs
(Medical Xpress)—If life were simple, a disease could be treated with one drug that hits one molecular target, like striking a piano key. Instead, researchers wrestle with the fact that most drugs hit multiple targets in ...
Mar 20, 2014
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Oncology & Cancer
Alternative target for breast cancer drugs
Scientists have identified higher levels of a receptor protein found on the surface of human breast tumour cells that may serve as a new drug target for the treatment of breast cancer. The results, which are published today ...
Jul 19, 2013
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Oncology & Cancer
Study identifies new drug target in deadly form of leukemia
A research team led by the Duke-NUS Graduate Medical School (Duke-NUS) in Singapore has identified ways to inhibit the function of a key protein linked to stem cell-like behavior in terminal-stage chronic myeloid leukemia ...
Jun 3, 2013
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Medical research
Discovery promises to improve drugs used to fight cancer, other diseases
(Medical Xpress)—Even when at rest, the human body is a flurry of activity. Like a microscopic metropolis locked in a state of perpetual rush hour traffic, the trillions of cells that make us who we are work feverishly ...
Jan 11, 2013
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Medical research
Novel test identifies patients most likely to benefit from ALK inhibition therapy
Approximately one in 20 patients with non-small cell lung carcinoma (NSCLC) has chromosomal aberrations targeting the anaplastic lymphoma kinase (ALK) gene. This has considerable implications for treatment because these patients ...
Dec 12, 2012
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Oncology & Cancer
Clinical trial delivers good results in leukemia patients
Huntsman Cancer Institute (HCI) researchers Michael Deininger, M.D., Ph.D., and Thomas O'Hare, Ph.D., were part of a team that found a potent oral drug, ponatinib, effective in patients who have developed resistance to standard ...
Nov 30, 2012
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Medications
Popular antidepressant might prevent heart failure
A medication usually used to help treat depression and anxiety disorders has the potential to help prevent heart failure, according to researchers at the University of Michigan.
Oct 1, 2012
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