Medications

Steroid drugs used for HRT can combat E. coli and MRSA

The emergence of drug-resistant bacteria is a global threat to human health, and the development of new antibiotics from scratch is an extremely expensive and time-consuming process. To address this urgent issue, researchers ...

Immunology

The 'switch' that keeps the immune system from attacking the body

A microscopic battle rages in our bodies, as our cells constantly fend off invaders through our immune system: a complex system of cells and proteins designed to protect us from harmful pathogens. One of its central components ...

Medical research

How does HIV get into the cell's center to kickstart infection?

UNSW medical researcher Dr. David Jacques and his team have discovered how the human immunodeficiency virus (HIV) breaches the cell nucleus to establish infection, a finding that has implications beyond HIV biology.

Diseases, Conditions, Syndromes

Researchers trace a form of lupus back to a single mutation

Sometimes a single mutation in our genetic make-up is enough to cause disease. This is also the case with the autoimmune disease lupus. Lupus causes severe inflammation throughout the body and can have a serious impact on ...

Diseases, Conditions, Syndromes

Possible trigger of chronic inflammatory bowel disease identified

As the cause of chronic inflammatory bowel diseases (IBD) such as Crohn's disease or ulcerative colitis is not yet known, treatment for sufferers is currently aimed at alleviating the often agonizing symptoms. The discovery ...

Oncology & Cancer

The role of p53 as a target for novel cancer therapies

The p53 tumor suppressor protein is encoded by TP53, the most frequently mutated gene in cancer. A review article published in Nature Reviews Clinical Oncology by Professor Klas G Wiman and colleagues at the Department of ...

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