A cohort study found that class I HLA evolutionary divergence (HED) of the donor predicts acute or chronic rejection of a liver transplant. This prognostic marker can be found rapidly at no additional cost and has the potential ...
Aug 24, 2021
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Innate or acquired resistance to current standard-of-care therapies is a major hindrance to successful chemotherapeutic intervention. There is a critical need to elucidate the underlying mechanisms responsible for chemoresistance ...
Mar 1, 2018
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Patients with gallbladder cancer often show few or no symptoms for long periods of time. As a result, the tumours are only detected at a late stage of the disease when treatment is often no longer possible. Working in collaboration ...
Oct 25, 2017
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A research team at the University of Basel's Biozentrum has investigated the expression of ribosomal proteins in a wide range of human tissues including tumors and discovered a cancer type specific signature. As the researchers ...
Dec 5, 2016
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(HealthDay)—Octamer-binding transcription factor 4 (Oct4) is a predictive marker for patients with digestive system cancers, according to a review and meta-analysis published online Nov. 7 in the Journal of Gastroenterology ...
Nov 22, 2016
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(HealthDay)—The mediator subunit MED15 appears to be involved in head and neck squamous cell carcinoma (HNSCC), according to a study published in the April issue of The American Journal of Pathology.
Apr 2, 2015
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(HealthDay)—The oncogenic microRNA (miRNA) miR-21 is a potential biomarker for detection and prognosis of colorectal cancer (CRC), according to a study published in the June 19 issue of the Journal of the National Cancer ...
Jun 20, 2013
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Even while being dragged to its destruction inside a cell, a cancer-promoting growth factor receptor fires away, sending signals that thwart the development of tumor-suppressing microRNAs (miRNAs) before it's dissolved, researchers ...
May 23, 2013
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A study has identified microRNA-155 as a new independent prognostic marker and treatment target in patients with acute myeloid leukemia that has normal-looking chromosomes under the microscope (that is, cytogenetically normal ...
May 13, 2013
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(HealthDay)—Life expectancy of people with aggressive brain cancer may be easier to determine with a new method under development at the University of Alabama at Birmingham, researchers say.
Apr 10, 2013
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