Diseases, Conditions, Syndromes

Discovery provides new insight into severe liver disease

Primary sclerosing cholangitis (PSC) is a severe and chronic liver disease. It affects men more than women, and most people who are diagnosed with PSC are between 30 and 40 years old.

Medical research

Bile duct function and disease highlighted in new study

Research from the Gupta Lab provides important insights into the extrahepatic bile ducts. These bile ducts outside of the liver are a critical but poorly understood component of the human digestive system. The study, led ...

Diseases, Conditions, Syndromes

Researchers link environmental exposures to liver disease

Mayo Clinic researchers have identified a diverse range of environmental chemicals in human bile in patients with primary sclerosing cholangitis, a rare, chronic liver disease of the bile ducts. The study, published in Exposome, ...

Diseases, Conditions, Syndromes

Q&A: How to manage symptoms of liver disease

DEAR MAYO CLINIC: My husband is 45 and has lived with irritable bowel syndrome for many years. He was recently diagnosed with primary sclerosing cholangitis. Are these two conditions related? We were told a liver transplant ...

Genetics

Genetic cause of severe liver disease discovered

Primary sclerosing cholangitis, or PSC, is a rare chronic inflammatory disease of the bile ducts. It normally debuts in young adults and two thirds of patients are men. In most cases, the patient also has an inflammatory ...

Surgery

Older donors may mean shorter queues to get a new liver

Imagine that you have just been told that you need a new liver. An operation may save your life. The waiting list is long, however, and it is uncertain when you will be able to get a transplant. This is reality for many thousands ...

Inflammatory disorders

Increased mortality in children with inflammatory bowel disease

Children who develop inflammatory bowel disease (ulcerative colitis or Crohn's disease) have an increased risk of death, both in childhood and later in life, a study from Karolinska Institutet published in the journal Gastroenterology ...

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