Oncology & Cancer

Appendiceal cancer gets its own preclinical model

Appendiceal cancer (malignancies of the appendix, a small tissue pouch that is part of the gastrointestinal tract) is very rare, occurring in perhaps one or two people per 1 million per year. Prognoses are mixed, with a 5-year ...

Oncology & Cancer

Improving interferon therapy for blood cancers

[Northwestern Medicine investigators have discovered a novel signaling pathway activated by interferons, a group of immune system proteins, that suppresses the anti-tumor response of interferons in patients with a particular ...

Oncology & Cancer

Improving leukemia therapy with targeted treatment approaches

In chronic leukemias, blocking the overactive kinase JAK2 by a targeted therapy approach is only mitigating the patients' symptoms, but cannot truly change the course of the disease. A study by the University of Basel has ...

Oncology & Cancer

Hematoxylin as a killer of CALR mutant cancer cells

Patients with myeloproliferative neoplasm (MPN), a group of malignant diseases of the bone marrow, often have a carcinogenic mutated form of the calreticulin gene (CALR). Scientists of the research group of Robert Kralovics, ...

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Neoplasm

Neoplasm is an abnormal mass of tissue as a result of neoplasia. Neoplasia ("new growth" in Greek) is the abnormal proliferation of cells. The growth of neoplastic cells exceeds and is not coordinated with that of the normal tissues around it. The growth persists in the same excessive manner even after cessation of the stimuli. It usually causes a lump or tumor. Neoplasms may be benign, pre-malignant (carcinoma in situ) or malignant (cancer).

In modern medicine, the term tumor means a neoplasm that has formed a lump. In the past, the term tumor was used differently. Some neoplasms do not cause a lump.

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