Diseases, Conditions, Syndromes

iPSC-derived kidney organoids to model a lifelong renal disease

Researchers have generated induced pluripotent stem cell (iPSC)-derived kidney organoids to model Alport syndrome caused by a mutation in the COL4A5 gene and have demonstrated the utility of a chemical chaperone to rescue ...

Genetics

Researchers reverse hearing loss in mice

New research from The Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London has successfully reversed hearing loss in mice.

Genetics

Researchers create mutant mice to study bipolar disorder

Bipolar disorder (BD) is a debilitating condition characterized by alternating states of depression (known as depressive episodes) and abnormal excitement or irritability (known as manic episodes). Large-scale genome-wide ...

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