In humans, the exact same mutation in a specific gene can produce widely different outcomes. It's a bit like adding the same amount of salt to different recipes—the effect on the finished dish can be quite different, depending ...
Apr 3, 2024
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Nearly two dozen experimental therapies targeting the immune system are in clinical trials for Alzheimer's disease, a reflection of the growing recognition that immune processes play a key role in driving the brain damage ...
Mar 8, 2023
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In two separate studies, researchers at EPFL have carried out extensive tests to develop the best mouse models for studying kidney and liver diseases. The findings provide crucial insights into both conditions, and are expected ...
Feb 21, 2023
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Scientists at Children's Hospital of Philadelphia (CHOP) have identified two proteins that could be used for a potential vaccine against nontypeable Haemophilus influenzae (NTHi). Working in a mouse model, the investigators ...
Aug 2, 2021
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Microbial communities in the intestine—also known as the gut microbiome—are vital for human digestion, metabolism and resistance to colonization by pathogens. The gut microbiome composition in infants and toddlers changes ...
May 8, 2020
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In an article published in Scientific Reports, researchers affiliated with the University of São Paulo (USP) in Brazil describe experiments performed with mice that show how genetic factors can determine whether an individual ...
Mar 25, 2020
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Congenic mouse strains—used for decades in immunology research and assumed to be genetically identical outside of a marker locus—have been found to contain previously unrecognized genetic variation, University of Alabama ...
Jan 27, 2020
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Due to strain-specific behavioral idiosyncrasies, inbred mouse strains are suboptimal research models for behavioral aging studies.
Oct 11, 2019
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Infectious proteins called prions cause a group of related, fatal and incurable neurodegenerative disorders, including bovine spongiform encephalopathy or Mad Cow disease and Creutzfeldt-Jakob disease, both of which affect ...
Jun 11, 2019
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90
Tumors arise when cells shake off their restraints and start to multiply out of control. But how fast a tumor grows does not depend solely on how quickly the cancer cells can divide, a new study has found.
May 30, 2019
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