A mutated protein expressed in lysosomes may contribute to Parkinson's disease, according to a new Northwestern Medicine study published in the Journal of Cell Biology.
Mar 12, 2024
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Our movements are controlled by multiple neural pathways that connect the brain and spinal cord. In particular, neurons in the cerebral cortex send commands to the motor neurons in the spinal cord and then to the muscles, ...
Aug 18, 2023
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Even mild COVID-19 can cause structural and functional alterations in the brain that may lead to neuropsychiatric disorders, such as anxiety, depression, fatigue and somnolence, as well as adverse effects on well-being, health ...
Jun 30, 2023
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Researchers have uncovered signature metabolites—much like fingerprints in the blood—linked to the cognitive dysfunction and impaired motor skills associated with medical cannabis treatment.
Apr 20, 2022
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A research team from Kumamoto University, Japan has developed an animal model that reproduces motor dysfunction and cerebellar neurodegeneration similar to that in spinocerebellar ataxia (SCA) by inhibiting chaperone-mediated ...
Sep 23, 2020
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It was when Xinglong Wang, PhD, received a call from a desperate father of a middle-aged son with amyotrophic lateral sclerosis (ALS) that he realized the extraordinary importance of his work. "Can you help save my son's ...
Jan 23, 2017
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Charcot-Marie-Tooth disease is an inherited disorder that leads to a gradual loss of motor neurons and, eventually, paralysis. The condition is caused by genetic mutations that disrupts cells' energy factories, called mitochondria. ...
Oct 24, 2016
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Michigan State University researchers used an old-fashioned neurobiology technique to explore new avenues for treatments to reverse a late-onset neurodegenerative disease that robs men of the capacity to walk, run, chew and ...
May 6, 2016
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(Medical Xpress)—Neurobiologist from the Friedrich Miescher Institute for Biomedical Research proved that excitability protects motoneurons from degeneration in amyotropic lateral sclerosis, a rare neurodegenerative disease. ...
Oct 3, 2013
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Perelman School of Medicine researchers at the University of Pennsylvania report the first biomarker results reported from the Parkinson's Progression Markers Initiative (PPMI), showing that a comprehensive test of protein ...
Aug 26, 2013
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