A new study published in Nature Communications provides direct evidence that antidepressant use during pregnancy can impact a child's brain development and contribute to the risk of mental health disorders later in life.
Feb 16, 2024
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A recent study, published in Neuropsychopharmacology, conducted by researchers from the University of Helsinki and the University of Eastern Finland, sheds light on the mechanisms of neural plasticity induced by the antidepressant ...
Apr 5, 2023
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Fluoxetine, a common antidepressant, inhibits the SARS-CoV-2 coronavirus in cell cultures and in preparations from human lung tissue. This was demonstrated by researchers at Julius-Maximilians-Universität (JMU) Würzburg ...
Aug 17, 2022
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As mental health professionals are grappling with a wave of pandemic-related anxiety and depression, a physician-researcher at The University of Toledo College of Medicine and Life Sciences is studying whether a commonly ...
Feb 19, 2021
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The antidepressant fluoxetine has been suggested as a means to improve brain recovery after acute stroke. However, a large randomized study on stroke patients at 35 Swedish hospitals shows that the drug has no such effect. ...
Jul 21, 2020
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A large international trial has confirmed previous findings that a commonly used antidepressant is not effective in supporting the recovery of patients who have had a stroke.
May 14, 2020
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In an analysis of primary care records of 519,513 UK adults who were overweight or obese between 2000-2016 and followed up until 2019, the incidence of new cases of depression was 92 per 10,000 people per year. The risk of ...
Apr 8, 2020
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Prozac, the trade name for the drug fluoxetine, was introduced to the U.S. market for the treatment of depression in 1988. Thirty years later, scientists still don't know exactly how the medication exerts its mood-lifting ...
Jul 10, 2019
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An international team led by Duke-NUS Medical School has found a potential link between autistic-like behaviour in adult mice and exposure to a common antidepressant in the womb. They also identified a treatment that helped ...
Apr 30, 2019
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When University of Ottawa biologists Marilyn Vera-Chang and Vance Trudeau began to study the effects of a popular antidepressant on reproduction levels in zebrafish, they stumbled across something that changed the course ...
Dec 11, 2018
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Fluoxetine (also known by the tradenames Prozac, Sarafem, Fontex) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is manufactured and marketed by Eli Lilly and Company. In combination with olanzapine it is known as Symbyax.
Fluoxetine is approved for the treatment of major depression (including pediatric depression), obsessive-compulsive disorder (in both adult and pediatric populations), bulimia nervosa, panic disorder and premenstrual dysphoric disorder.
Despite the availability of newer agents, fluoxetine remains extremely popular. In 2010, over 24.4 million prescriptions for generic formulations of fluoxetine were filled in the United States alone, making it the third most prescribed antidepressant after sertraline (SSRI; became generic in 2006) and citalopram (SSRI; became generic in 2003) in that country.
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