Surgery

New strategies for engineering stable articular cartilage

A new study assesses the effect of the gremlin-1 (GREM1) protein on the in vitro and in vivo stability of bone marrow stem cell (BMSC)-derived cartilage engineered within scaffolds. The study design and results are reported ...

Arthritis & Rheumatism

Chemical stimuli can support growing of stable cartilage cells

Cell-based therapies could offer a way to treat cartilage injuries before the ultimate damage of osteoarthritis on articular cartilage. Cartilage-derived chondrocytes can be used for cartilage repair, but the expanded cells ...

Arthritis & Rheumatism

High-fat diet improves cartilage repair in mice

Obesity is a well-known risk factor for osteoarthritis, but its effects on cartilage repair are unknown. In a recent study in a mouse model of cartilage repair, a high-fat diet and increased body weight did not negatively ...

Medical research

Repair cartilage potentially can heal horribly broken bones

Stem cells could one day be stimulated to make a special type of cartilage to help repair large, hard-to-heal bone fractures – a potential boon for doctors treating big-money athletes, USC researchers say.

Arthritis & Rheumatism

Resolvin D1 ameliorates inflammatory arthritis in mouse model

Rheumatoid arthritis (RA) is a debilitating autoimmune disorder that is characterized by the accumulation of inflammatory cells within the fluid of the joints. Current therapeutic strategies mostly serve to ease pain and ...

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