Medical research

Mutations, CRISPR, and the biology behind movement disorders

Scientists at the RIKEN Center for Brain Science (CBS) in Japan have discovered how mutations related to a group of movement disorders produce their effects. Published in Proceedings of the National Academy of Sciences, the ...

Diabetes

Cellular calcium handling in diabetes

Tight regulation of calcium levels in the endoplasmic reticulum (ER) – a cellular organelle with multiple functions – contributes to insulin secretion by pancreatic beta cells. Although ER calcium handling is perturbed ...

Neuroscience

Scientists find sensor that makes synapses fast

Synapses, the connections between neurons, come in different flavors, depending on the chemical they use as transmitter. Signal transmitters, or neurotransmitters, are released at the synapse after calcium ions flow into ...

Medical research

Calcium channels team up to activate excitable cells

Voltage-gated calcium channels open in unison, rather than independently, to allow calcium ions into and activate excitable cells such as neurons and muscle cells, researchers with UC Davis Health System and the University ...

Diabetes

Mechanism behind age-dependent diabetes discovered

Ageing of insulin-secreting cells is coupled to a progressive decline in signal transduction and insulin release, according to a recent study by researchers at Karolinska Institutet in Sweden. The finding, which is published ...

Cardiology

Understanding heart failure at the cellular level

A team of researchers at the University of Florence in Italy and the University of Connecticut Health Center have used a multidisciplinary approach to provide an unprecedented glimpse of what happens to the heart during an ...

Medical research

Researchers solve 20-year puzzle of how heart regulates its beat

(Medical Xpress)—A 20-year puzzle as to how the heart regulates contraction appears to have been solved by researchers from the University of Bristol. The findings, published in the journal Biophysics, paves the way to ...

Medical research

Study shows ultrasound triggers bone cell mobility

Research led by Yi-Xian Qin, PhD, Professor, Department of Biomedical Engineering, and Director of the Orthopaedic Bioengineering Research Laboratory at Stony Brook University, demonstrated that the use of medium-intensity ...

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