HIV & AIDS
Researchers develop new method to 'fingerprint' HIV
HIV is a master of disguise. The virus uses a shield of sugar molecules, called glycans, to hide from the immune system and block antibodies from attacking it.
Mar 28, 2017
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News tagged with broadly neutralizing antibodies
HIV & AIDS
Researchers map pathways to protective antibodies for an HIV vaccine
A Duke Health-led research team has described both the pathway of HIV protective antibody development and a synthetic HIV outer envelope mimic that has the potential to induce the antibodies with vaccination.
Mar 15, 2017
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HIV & AIDS
Encouraging clinical results for an antibody drug to prevent or treat HIV
A new biologic agent—the most potent of its kind so far—is showing early promise as part of a potential new strategy for treating HIV. The drug, known as 10-1074, may also offer a new way to prevent viral infection in ...
Feb 6, 2017
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HIV & AIDS
Antibody combination puts HIV on the ropes
Without antiretroviral drug treatment, the majority of people infected with HIV ultimately develop AIDS, as the virus changes and evolves beyond the body's ability to control it. But a small group of infected individuals—called ...
Jan 25, 2017
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HIV & AIDS
Broadly neutralizing HIV antibodies pave the way for vaccine
A small number of people infected with HIV produce antibodies with an amazing effect: Not only are the antibodies directed against the own virus strain, but also against different sub-types of HIV that circulate worldwide. ...
Sep 26, 2016
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HIV & AIDS
Training human antibodies to protect against HIV
During HIV infection, the virus mutates too rapidly for the immune system to combat, but some people produce antibodies that can recognize the virus even two years after infection. With an eye towards developing a vaccine, ...
Sep 8, 2016
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HIV & AIDS
Broadly neutralizing HIV antibodies engineered to be better vaccine leads
One approach to HIV vaccine development relies on broadly neutralizing antibodies (bnAbs) that protect against different circulating HIV strains. bnAbs have been isolated from HIV-infected individuals, but they are highly ...
Aug 25, 2016
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HIV & AIDS
Scientists identify immunological profiles of people who make powerful HIV antibodies
One of the main mysteries confounding development of an HIV vaccine is why some people infected with the virus make the desired antibodies after several years, but a vaccine can't seem to induce the same response.
Jul 29, 2016
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HIV & AIDS
Researchers find alternative pathways to HIV antibodies
The immune system appears to hamper an investigational vaccine from inducing antibodies that protect against HIV infection, but there may be ways to overcome this impediment, according to research led by the Duke Human Vaccine ...
May 4, 2016
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HIV & AIDS
Findings in humans provide encouraging foundation for upcoming AIDS vaccine clinical trial
Some people infected with HIV naturally produce antibodies that effectively neutralize many strains of the rapidly mutating virus, and scientists are working to develop a vaccine capable of inducing such "broadly neutralizing" ...
Mar 24, 2016
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