Dementia treatments linked with serious side effects: Study
Several antipsychotic treatments given to patients with dementia have been linked to serious side effects including heart failure, a study published Thursday has found.
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Several antipsychotic treatments given to patients with dementia have been linked to serious side effects including heart failure, a study published Thursday has found.
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Overuse of marijuana is increasingly being linked to dangerous bouts of psychosis, and a new study finds that antipsychotics may be needed to keep such patients out of the hospital.
Apr 5, 2024
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For people living with serious mental illnesses like schizophrenia or bipolar disorder, standard treatment with antipsychotic medications can be a double-edged sword. While these drugs help regulate brain chemistry, they ...
Apr 1, 2024
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Researchers from the University of Liverpool are calling for policy reform in the management of antipsychotic medication (APM) to support both patients and health care professionals.
Mar 4, 2024
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Frontotemporal dementia (FTD) is a group of neurologic disorders associated with changes in personality, behavior, language or movement. Some FTD forms are inherited, and some are not. Typically, people develop FTD symptoms ...
Feb 26, 2024
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As interest in psychedelics has grown, so has interest in ways to end a bad trip. Recent research reveals that people are giving potentially dangerous advice on social media on how to stop a trip that is less than pleasurable.
Feb 15, 2024
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An intensive meditation-based intervention (iMI) significantly improves positive symptoms, particularly refractory hallucinations and delusions, in male patients with schizophrenia, according to a study published online on ...
Feb 14, 2024
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As director of the Program for Early Assessment, Care, and Study (PEACS), a University of Colorado Department of Psychiatry clinic that focuses on young people at risk of psychotic disorders, Michelle West, Ph.D., has seen ...
Jan 23, 2024
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The use of the antipsychotic drugs quetiapine and haloperidol is associated with an increased risk of ventricular arrhythmias and sudden cardiac death (SCD) caused by drug-induced QT prolongation, reports a new study in Heart ...
Jan 15, 2024
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Marking a substantial advancement in understanding obsessive-compulsive disorder (OCD), researchers from Zhejiang University School of Medicine have revealed key connections between clinical characteristics, neuroimaging ...
Jan 9, 2024
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An antipsychotic (or neuroleptic) is a tranquilizing psychiatric medication primarily used to manage psychosis (including delusions or hallucinations, as well as disordered thought), particularly in schizophrenia and bipolar disorder. A first generation of antipsychotics, known as typical antipsychotics, was discovered in the 1950s. Most of the drugs in the second generation, known as atypical antipsychotics, have been developed more recently, although the first atypical antipsychotic, clozapine, was discovered in the 1950s and introduced clinically in the 1970s. Both generations of medication tend to block receptors in the brain's dopamine pathways, but antipsychotic drugs encompass a wide range of receptor targets.
A number of harmful and undesired (adverse) effects have been observed, including lowered life expectancy, weight gain, decrease in brain volume, enlarged breasts and milk discharge in men and women (hyperprolactinaemia), lowered white blood cell count (agranulocytosis), involuntary repetitive body movements (tardive dyskinesia), diabetes, an inability to sit still or remain motionless (akathisia), sexual dysfunction, a return of psychosis requiring increasing the dosage due to cells producing more neurochemicals to compensate for the drugs (tardive psychosis), and a potential for permanent chemical dependence leading to psychosis much worse than before treatment began, if the drug dosage is ever lowered or stopped (tardive dysphrenia).[citation needed]
Temporary withdrawal symptoms including insomnia, agitation, psychosis, and motor disorders may occur during dosage reduction of antipsychotics, and can be mistaken for a return of the underlying condition.
The development of new antipsychotics with fewer of these adverse effects and with greater relative effectiveness as compared to existing antipsychotics (efficacy), is an ongoing field of research.
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